Background：This gene encodes a member of the protein inhibitor of activated STAT （PIAS） family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：AR interacting protein,DDXBP1,DEAD/H （Asp-Glu-Ala-Asp/His） box binding protein 1,DEAD/H box binding protein 1,DEAD/H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu binding protein,Gu-binding protein,GU/RH-II,Pias1,PIAS1,Protein inhibitor of activated STAT protein 1,Protein inhibitor of activated STAT,1,RNA helicase II binding protein,RNA helicase II-binding protein,Zinc finger,MIZ-type containing 3,ZMIZ3
Host：Rabbit
Reactivity：Human,Mouse
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human PIAS1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：200
Gene_ID（human）：8554
Swissprot：O75925
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
