Background：This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
仕様
Synonyms：hSIRT 3,hSIRT3,Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase,NAD dependent deacetylase sirtuin 3 mitochondrial,NAD-dependent protein deacetylase sirtuin-3,mitochondrial,Regulatory protein SIR2 homolog 3,Silent mating type information regulation 2 S.cerevisiae homolog 3,Sir 2 like 3,SIR 2 like protein 3,SIR 3,SIR2 L3,Sir2 like 3,SIR2 like protein 3,SIR2-like protein 3,SIR2L3,SIR3,SIRT 3,SIRT3,Sirtuin 3,Sirtuin silent mating type information regulation 2 homolog 3 （S. cerevisiae）,Sirtuin type 3,Sirtuin3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human SIRT3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：1000 IHC1：20 - 1：50
Gene_ID（human）：23410
Swissprot：Q9NTG7
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
