Background:The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:3 hydroxyacyl CoA dehydrogenase,3,2 trans enoyl CoA isomerase,3-hydroxyacyl-CoA dehydrogenase,ECHD,ECHP,EHHADH,Enoyl Coenzyme A,hydratase/3 hydroxyacyl Coenzyme A dehydrogenase,L 3 hydroxyacyl CoA dehydrogenase,L bifunctional protein,peroxisomal,L PBE,LBFP,LBP,MGC120586,MS730,PBE,PBFE,Peroxisomal bifunctional enzyme,Peroxisomal enoyl CoA hydratase
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human EHHADH
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):1962
Swissprot:Q08426
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction