Background：This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms：Chloride channel protein 5,Chloride channel voltage sensitive 5,Chloride transporter ClC-5,ClC-5,CLC5 ,CLCK2,CLCN5,CLCN5,DENTS,H（+）/Cl（-） exchange transporter 5,hCIC-K2,NPHL1,NPHL2,Voltage gated chloride ion channel CLCN5,XLRH,XRN
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CLCN5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：1184
Swissprot：P51795
Isotype：IgG
Research Areas：Metabolism, Neuroscience, Signal transduction
