Background:The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms:FLJ42816,HSPC082,KIAA0569,SIP 1,SIP1,Smad-interacting protein 1,SMADIP 1,SMADIP1,ZEB 2,Zeb2,ZEB2,Zfhx1b,ZFHX1B protein,Zfx1b,Zinc finger E box binding protein 2,Zinc finger E-box-binding homeobox 2,Zinc finger homeobox 1b,zinc finger homeobox protein 1,Zinc finger homeobox protein 1b
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human ZEB2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):9839
Swissprot:O60315
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience, Stem cells