Background：The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Abundant SRC homology,Adapter protein GRB2,ASH,Ash protein,EGFRBP GRB2,Epidermal growth factor receptor binding protein,Epidermal growth factor receptor binding protein GRB2,GRB 2,GRB2 adapter protein,Grb2,GRB2,Grb3 3,Growth factor receptor bound protein 2,Growth factor receptor bound protein 3,Growth factor receptor-bound protein 2,HT027,MST084,MSTP084,NCKAP2,OTTHUMP00000166096,OTTHUMP00000166097,OTTHUMP00000166098,Protein ash,SEM5,SH2/SH3 adapter GRB2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human GRB2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
