Background：The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
仕様
Synonyms：FLJ20032,KIAA1546,MDS,Methylcytosine dioxygenase TET2,Nbla00191,Probable methylcytosine dioxygenase TET2,Protein Ayu17 449,Tet 2,Tet methylcytosine dioxygenase 2,Tet oncogene 2,Tet oncogene family member 2,TET2,TET2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TET2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：100 - 1：200
Gene_ID（human）：54790
Swissprot：Q6N021
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
