Background：The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
仕様
Synonyms：Divergent upstream protein,DNA mismatch repair protein,DNA mismatch repair protein Msh 3,DNA mismatch repair protein MSH3,DUC 1,DUC1,DUG,DUP,hMSH3,MGC163306,MGC163308,Mismatch repair protein 1,MRP 1,MRP1,MSH 3,MSH3,MSH3,MutS homolog 3 （E. coli）,MutS homolog 3
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MSH3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
