Background：The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
仕様
Synonyms：MDS1 And EVI1 Complex Locus,Ecotropic Virus Integration Site 1 Protein Homolog,Myelodysplasia Syndrome-Associated Protein 1,PR Domain 3,EVI1,MDS1,MDS1 And EVI1 Complex Locus Protein EVI1,MDS1 And EVI1 Complex Locus Protein MDS1,Ecotropic Viral Integration Site 1,Myelodysplasia Syndrome 1 Protein,Myelodysplasia Syndrome 1,AML1-EVI-1 Fusion Protein,Zinc Finger Protein Evi1,Oncogene EVI1,AML1-EVI-1,MDS1-EVI1,RUSAT2,KMT8E,PRDM3,EVI-1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MECOM
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
