Background：This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：NKX2.5, mouse, homolog of,Cardiac-specific homeobox 1,Cardiac-specific homeobox,CHNG5,CSX,CSX1,FLJ52202,FLJ97166,FLJ97195,FLJ97197,FLJ99536,HLHS2,Homeobox protein CSX,Homeobox protein NK-2 homolog E,Homeobox protein Nkx 2.5,Homeobox protein Nkx-2.5,NK2 homeobox 5,NK2 transcription factor related locus 5,NK2 transcription factor related, locus 5 （Drosophila）,NK2, Drosophila, homolog of, E,NKX2-5,NKX2.5,NKX25,Nkx2E,NKX4-1,Tinman paralog,VSD3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NKX2-5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：1482
Swissprot：P52952
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Developmental biology, Neuroscience, Stem cells
