Background:This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:ERGB transcription factor,Ewing Sarcoma breakpoint region 2,EWSR 2,EWSR2,FLI 1,FLI 1 proto oncogene,Fli-1 proto-oncogene,ETS transcription factor,FLI1,FLI1 EWS fusion gene,FLI1 proto oncogene,FLI1,Friend leukemia integration 1 (FLI1) transcription factor,Friend leukemia integration 1 transcription factor,Friend leukemia virus integration 1,Proto-oncogene Fli-1,Sarcoma breakpoint region 2 (EWSR2),SIC 1,SIC1,Transcription factor ERGB,Viral integration region FLI1,Viral integration region FLI1,mouse,homolog of
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human FLI1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.