Background：This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine （C-C motif） receptor 5 （CCR5）, and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
仕様
Synonyms：Beta chemokine RANTES,Beta chemokine RANTES precursor,C C motif chemokine 5,CCL 5,CCL5,CCL5,Chemokine （C C motif） ligand 5,Chemokine CC Motif Ligand 5,D17S136E,EoCP,Eosinophil chemotactic cytokine,MGC17164,RANTES（4-68）,Regulated upon activation normally T expressed and presumably secreted,SCYA 5,SCYA5,SIS delta,SIS-delta,SISd,Small inducible cytokine A5 （RANTES）,Small inducible cytokine A5,Small inducible cytokine subfamily A （Cys Cys） member 5,Small-inducible cytokine A5,T cell specific protein p288 ,T cell specific RANTES protein,T cell-specific protein P228,T-cell-specific protein RANTES,TCP 228,TCP228
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CCL5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
