Background：The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
仕様
Synonyms：BDB,BDB1,Brachydactyly type B,EC 2.7.10.1,MGC163394,Neurotrophic tyrosine kinase,Neurotrophic tyrosine kinase, receptor related 2 ,NTRKR2,Receptor tyrosine kinase-like orphan receptor 2,receptor-related 2,ROR2,ROR2,Tyrosine protein kinase transmembrane receptor ROR2 ,Tyrosine-protein kinase transmembrane receptor Ror2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human ROR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4920
Swissprot：Q01974
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
