Background:Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
仕様
Synonyms:BAP 1,BAP1,DING,DinG protein,E3 ubiquitin protein ligase RING 2,E3 ubiquitin protein ligase RING2,E3 ubiquitin-protein ligase RING2,HIP2 interacting protein 3,HIP2-interacting protein 3,HIPI 3,HIPI3,Huntingtin interacting protein 2 interacting protein 3,Huntingtin-interacting protein 2-interacting protein 3,OTTHUMP00000060668,Polycomb M33 interacting protein Ring 1B,Polycomb M33 interacting protein Ring1B,Protein DinG,RING 1B,RING 2,RING finger protein 1B,RING finger protein 2,RING finger protein BAP 1,RING finger protein BAP-1,RING finger protein BAP1,RING1b,RING2,RNF 2,Rnf2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human RNF2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.