Background：Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms （L and T） have been identified. Plastin 1 （otherwise known as Fimbrin） is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential （fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.）. However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
仕様
Synonyms：CP64,L plastin,L-plastin,Larval cuticle protein 1,LC64P,LCP-1,LCP1,LPL,Lplastin,Lymphocyte cytosolic protein 1,Plastin 2,Plastin-2,PLS2,PLSL
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human LCP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IP1：20 - 1：50
Gene_ID（human）：3936
Swissprot：P13796
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
