Background:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
仕様
Synonyms:36B4,60S acidic ribosomal protein P0,60S ribosomal protein L10E,Acidic ribosomal phosphoprotein P0,Arbp,L10E,LP0,MGC107165,MGC107166,MGC111226,MGC88175,OTTMUSP00000015585,P0,PRLP0,Ribosomal phosphoprotein,acidic,P0,Ribosomal protein P0,Ribosomal protein,large,P0,RLA0,rplP0,RPP0
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RPLP0
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):6175
Swissprot:P05388
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling