Background:This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
仕様
Synonyms:alpha pal,alpha palindromic binding protein,Alpha palindromic-binding protein,Alpha-pal,locus control region factor 1,NFE2 related factor 1,NRF-1,Nrf1,NRF1,Nuclear respiratory factor 1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human NRF1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):4899
Swissprot:Q16656
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism