Background：The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes： ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
仕様
Synonyms：Cyclin selective ubiquitin carrier protein,dJ447F3.2,Mitotic specific ubiquitin conjugating enzyme,UB E2C,UBCH 10,UbcH10,UBE 2C,Ube2c,UBE2C,Ubiquitin carrier protein C,Ubiquitin carrier protein E2 C,Ubiquitin carrier protein E2C,Ubiquitin conjugating enzyme E2 C,Ubiquitin conjugating enzyme E2C,Ubiquitin protein ligase C,Ubiquitin-conjugating enzyme E2 C,Ubiquitin-protein ligase C
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,IF,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human UBE2C
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
