Background:The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
仕様
Synonyms:A1 37,A1 37 kDa subunit,Activator 1 37,Activator 1 37 kDa subunit,Activator 1 subunit 4,Replication factor C 37,Replication factor C 37 kDa subunit,Replication factor C subunit 4,Replication factor C4,RF-C 37 kDa subunit,RFC 37,RFC37,RFC4 replication factor C (activator 1)4 37kDa,RfC4,RFC4
Host:Rabbit
Reactivity:Human,Rat
Applications:WB,IHC,IF,IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human RFC4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.