Background：This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta （TGF-beta） superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：Activin A receptor type 1B,Activin A receptor type II like kinase 4,Activin A type 1B receptor,Activin A type IB receptor,Activin receptor like kinase 4,Activin receptor type 1B,Activin receptor type IB,Activin receptor type-1B,Activin receptor-like kinase 4,ACTR IB,ACTR-IB,ACTRIB,ACV1B,ACVR 1B,Acvr1b,ACVRLK 4,ACVRLK4,ALK 4,ALK-4,ALK4,Serine（threonine） protein kinase receptor R2,Serine/threonine-protein kinase receptor R2,SKR 2,SKR2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ACVR1B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：91
Swissprot：P36896
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
