Background：This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 （HSD10） deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
仕様
Synonyms：17 beta hydroxysteroid dehydrogenase 10,17 beta hydroxysteroid dehydrogenase type 10,17-beta-HSD 10,17-beta-hydroxysteroid dehydrogenase 10,17b HSD10,3 hydroxy 2 methylbutyryl CoA dehydrogenase,3 hydroxyacyl CoA dehydrogenase type 2,3 hydroxyacyl CoA dehydrogenase type II,3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3-hydroxyacyl-CoA dehydrogenase type-2,AB binding alcohol dehydrogenase,ABAD,Ads9,Amyloid beta binding polypeptide,Amyloid beta peptide binding alcohol dehydrogenase,Amyloid beta peptide binding protein,Amyloid beta peptide binding protein,CAMR,DUPXp11.22,Endoplasmic Reticulum Amyloid Binding Protein,Endoplasmic reticulum associated amyloid beta peptide binding protein,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,ER associated amyloid beta-binding protein,ERAB,HADH 2,HADH2,HCD 2,HCD2,HCD2,Hsd17b10,Hydroxyacyl CoA Dehydrogenase type II,Hydroxyacyl Coenzyme A dehydrogenase type II,Hydroxysteroid （17 beta） dehydrogenase 10,Mental retardation X linked syndromic 11,MHBD,Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,MRPP2,MRX17,SCHAD,SDR5C1,Short chain dehydrogenase/reductase family 5C member 1,Short chain L 3 hydroxyacyl CoA dehydrogenase type 2,Short chain type dehydrogenase/reductase XH98G2,Short-chain type dehydrogenase/reductase XH98G2,Type 10 17b HSD,Type 10 17beta hydroxysteroid dehydrogenase,Type II HADH,XH98G2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human HSD17B10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3028
Swissprot：Q99714
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Tags ＆ Cell Markers
