Background:This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
仕様
Synonyms:c MER,c mer proto oncogene tyrosine kinase,c-mer,cMER,cmer protooncogene tyrosine kinase,Eyk,MER,MER receptor tyrosine kinase,MERK,MERPEN,Mertk,MERTK c-mer proto-oncogene tyrosine kinase,MERTK,MGC133349,nmf12,Nyk,Proto oncogene tyrosine protein kinase MER,Proto oncogene tyrosine protein kinase MER precursor,Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK,RP38,STK kinase,Tyrosine-protein kinase Mer
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human MERTK
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):10461
Swissprot:Q12866
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction