Background：This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core （WFDC） domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters： centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
仕様
Synonyms：Cementoin,ELAF,Elafin,Elastase Specific Inhibitor,Elastase-specific inhibitor,ES 1,ESI,Peptidase inhibitor 3,Peptidase inhibitor 3, skin derived,PI 3,PI-3,PI3,Pre elafin,Protease inhibitor 3 skin derived ,Protease inhibitor 3, skin derived （SKALP）,Protease inhibitor WAP3,SKALP,Skin derived Anti leukoproteinase,Skin-derived antileukoproteinase,Trappin 2,WAP four disulfide core domain 14,WAP four disulfide core domain protein 14,WAP four-disulfide core domain protein 14,WAP3,WFDC14
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PI3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：100 - 1：200
Gene_ID（human）：5266
Swissprot：P19957
Isotype：IgG
Research Areas：Cancer, Cell Biology, Immunology, Microbiology
