Background:This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:AP 4 A synthetase,Charcot Marie Tooth neuropathy 2D,Charcot Marie Tooth neuropathy neuronal type D,CMT2D ,Diadenosine tetraphosphate synthetase,DSMAV ,EC 6.1.1.14,Glycine tRNA ligase,Glycyl tRNA synthetase,GlyRS ,HMN5,SMAD1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human GARS
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:1000 - 1:4000 IHC1:50 - 1:200
Gene_ID(human):2617
Swissprot:P41250
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling