Background：The product of this gene is a member of the receptor-interacting protein （RIP） family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor （TNF） receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
仕様
Synonyms：Receptor interacting protein 3,Receptor interacting serine threonine kinase 3,Receptor interacting serine/threonine protein kinase 3,Receptor-interacting protein 3,Receptor-interacting serine/threonine-protein kinase 3,RIP 3,RIP like protein kinase 3,RIP-3,RIP-like protein kinase 3,RIPK 3,RIPK3,RIPK3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of Human RIPK3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：11035
Swissprot：Q9Y572
Isotype：IgG
Research Areas：Cancer, Cell Biology, Immunology, Signal transduction
