Background：The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
仕様
Synonyms：C20orf97,Neuronal cell death inducible putative kinase,Neuronal cell death-inducible putative kinase,NIPK,p65 interacting inhibitor of NF-kappaB,p65-interacting inhibitor of NF-kappa-B,SINK,SKIP 3,SKIP3,TRB 3,TRB-3,TRB3,TRIB 3,Trib3,TRIB3,Tribbles homolog 3,Tribbles pseudokinase 3,Tribbles3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TRIB3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：57761
Swissprot：Q96RU7
Isotype：IgG
Research Areas：Cell Biology, Cardiovascular, Signal transduction
