Background:This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Aminoacyl L proline hydrolase,Imidodipeptidase,MGC10905,MGC95081,Pep 4,Pep4,pepD,PEPD,Peptidase 4,Peptidase D,Prolidase,Proline dipeptidase,X pro dipeptidase,X-Pro dipeptidase,Xaa-Pro dipeptidase
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PEPD
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):5184
Swissprot:P12955
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction