Background：This gene encodes two proteins： sterol carrier protein X （SCPx） and sterol carrier protein 2 （SCP2）, as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
仕様
Synonyms：DKFZp686C12188,DKFZp686D11188,NLTP,NLTP,Non-specific lipid-transfer protein,Nonspecific lipid transfer protein,NSL TP,NSL-TP,OTTHUMP00000010488,OTTHUMP00000231766,OTTHUMP00000231767,OTTHUMP00000231768,OTTHUMP00000231769,OTTHUMP00000231770,OTTHUMP00000231772,OTTHUMP00000231773,OTTHUMP00000231774,OTTHUMP00000231776,OTTHUMP00000234662,Propanoyl CoA C acyltransferase,Propanoyl-CoA C-acyltransferase,SCP 2,SCP chi ,SCP X,SCP-2,SCP-chi,SCP-X,SCP2,SCPchi ,SCPX,Sterol carrier protein 2,Sterol carrier protein X
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human SCP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：6342
Swissprot：P22307
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
