Background:This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
仕様
Synonyms:38kDa,AA672939,Cell cycle protein p38 2G4 homolog,Cell cycle protein p38-2G4 homolog,ErbB-3 binding protein 1,ErbB3 binding protein 1,ErbB3-binding protein 1,ErbB3-binding protein Ebp1,hG4 1,hG4-1,IRES-specific cellular trans-acting factor 45 kDa,MGC81621,MGC94070,Mpp1,p38 2G4,Pa2g4,PA2G4,Plfap,Proliferation associated 2G4,Proliferation associated 2G4,38-KD,Proliferation-associated 2G4,38kDa,Proliferation-associated 2G4,a,Proliferation-associated protein 1,Proliferation-associated protein 2G4,Protein p38-2G4,si:dz150i12.2,wu:fb19b11,wu:ft56d05,zgc:86732
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human PA2G4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.