Background：The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
仕様
Synonyms：BAF57,BRG1 associated factor 57,BRG1-associated factor 57,Chromatin remodeling complex BRG1 associated factor 57,FLJ35648,SMARCE 1,SMARCE1,SMCE1,SWI/SNF related matrix associated actin dependent regulator of chromatin e1,SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human SMARCE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
