Background：The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes.
仕様
Synonyms：MDA-9,MDA9,Melanoma differentiation-associated protein 9,Pro-TGF-alpha cytoplasmic domain-interacting protein 18,Scaffold protein Pbp1,SDCB1,SDCBP,ST1,SYCL,Syndecan binding protein （syntenin）,Syndecan binding protein 1,Syndecan-binding protein 1,Syntenin 1,Syntenin-1,TACIP18
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human SDCBP
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
