Background：This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仕様
Synonyms：ATP dependent DNA helicase VIII,ATP-dependent DNA helicase VIII,G3BP,G3BP stress granule assembly factor 1,G3BP-1,G3bp1,G3BP1,GAP binding protein,GAP SH3 domain binding protein 1,GAP SH3 domain-binding protein 1,GTPase activating protein （SH3 domain） binding protein 1,hDH VIII,Human DNA helicase VIII,MGC111040,Ras GTPase activating protein binding protein 1,Ras GTPase activating protein SH3 domain binding protein,Ras GTPase-activating protein-binding protein 1,RasGAP associated endoribonuclease G3BP
Host：Rabbit
Reactivity：Human,Mouse,Duck
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human G3BP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：10146
Swissprot：Q13283
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
