Background:This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
仕様
Synonyms:B61,ECKLG,EFL 1,EFL1,EFNA 1,Efna1,EFNA1,EPH related receptor tyrosine kinase ligand 1,EPH-related receptor tyrosine kinase ligand 1,Ephrin-A1,Ephrin-A1,secreted form,EphrinA1,EPLG 1,EPLG1,Immediate early response protein B61,LERK 1,LERK-1,LERK1,Ligand of eph related kinase 1,OTTHUMP00000033242,OTTHUMP00000033271,secreted form,TNF alpha-induced protein 4,TNFAIP 4,TNFAIP4,Tumor necrosis factor alpha induced protein 4,Tumor necrosis factor alpha-induced protein 4
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human EFNA1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):1942
Swissprot:P20827
Isotype:IgG
Research Areas:Cardiovascular, Neuroscience, Signal transduction