Background：The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
仕様
Synonyms：CAAF1,CAGC,Calcitermin,Calcium-binding protein in amniotic fluid 1,Calgranulin C,Calgranulin-C,Calgranulin-related protein,CGRP,EN RAGE,EN-RAGE,ENRAGE,Extracellular newly identified RAGE-binding protein,migration inhibitory factor-related protein 6,MRP6,Neutrophil S100 protein,p6,Protein S100 A12,S100 calcium binding protein A12,S100 calcium-binding protein A12 （calgranulin C）,S100 calcium-binding protein A12,S100A12,S10AC
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human S100A12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200
Gene_ID（human）：6283
Swissprot：P80511
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
