Background:This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.
仕様
Synonyms:Co chaperone p23,cPGES,Cytosolic prostaglandin E synthase,Cytosolic prostaglandin E2 synthase,Hsp90 co chaperone,Hsp90 co-chaperone,P23,Progesterone receptor complex,Progesterone receptor complex p23,Prostaglandin E synthase 3 (cytosolic),Prostaglandin E synthase 3,PTGES 3,PTGES3,Sid 3177,TEBP,TEBP,Telomerase binding protein p23,Telomerase-binding protein p23,Unactive progesterone receptor 23 kD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human PTGES3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):10728
Swissprot:Q15185
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction