Background:The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Carnitine O palmitoyltransferase 1 liver isoform,Carnitine O palmitoyltransferase I,Carnitine O palmitoyltransferase I liver isoform,Carnitine O-palmitoyltransferase 1,Carnitine O-palmitoyltransferase I,Carnitine palmitoyltransferase 1A (liver),Carnitine palmitoyltransferase 1A,Carnitine palmitoyltransferase I,Carnitine palmitoyltransferase I liver,CPT 1,CPT I,CPT1,CPT1 L,CPT1-L,Cpt1a,CPT1A,CPTI,CPTI-L,L CPT1,liver isoform
Host:Rabbit
Reactivity:Human,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human CPT1A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000 IF1:50 - 1:200
Gene_ID(human):1374
Swissprot:P50416
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction, Tags & Cell Markers