Background:The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
仕様
Synonyms:AD FSP,atl1,ATLA1,Atlastin GTPase 1,Atlastin-1,Atlastin1,Brain specific GTP binding protein,Brain-specific GTP-binding protein,FSP1,GBP-3,GBP3,GTP-binding protein 3,Guanine nucleotide-binding protein 3,Guanylate binding protein 3,hGBP3,HSN1D,Spastic paraplegia 3 protein A,SPG 3A,SPG3,SPG3A,SPG3A gene
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human ATL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.