Background：This gene encodes a GTPase-activating protein （GAP） that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
仕様
Synonyms：CYK4,GAP,Gap1,GTPase activating protein,HsCYK-4,ID GAP,KIAA1478,Male germ cell RacGap,MgcRacGAP,Protein CYK4 homolg,Protein CYK4 homolog,Rac GTPase activating protein 1,Rac GTPase-activating protein 1,RACGAP 1,Racgap1,RGAP1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human RACGAP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：29127
Swissprot：Q9H0H5
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
