Background：This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
仕様
Synonyms：hTRF1 AS,NIMA interacting protein 2,NIMA-interacting protein 2,PIN 2,PIN2,t TRF1,Telomeric protein Pin2,Telomeric protein Pin2/TRF1,Telomeric repeat binding factor （NIMA interacting） 1,Telomeric repeat binding factor 1,Telomeric repeat binding protein 1,Telomeric repeat-binding factor 1,TERF 1,Terf1,TERF1,TRBF 1,TRBF1,TRF 1,TRF,TTAGGG repeat binding factor 1,TTAGGG repeat-binding factor 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TERF1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：7013
Swissprot：P54274
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Tags ＆ Cell Markers
