Background：This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.
仕様
Synonyms：APP beta secretase,Asp 2,ASP2,Aspartyl protease 2,BACE 1,BACE,BACE1,BACE1,Beta secretase 1,Beta secretase,Beta site amyloid beta A4 precursor protein cleaving enzyme,Beta site amyloid precursor protein cleaving enzyme 1,Beta site amyloid precursor protein cleaving enzyme,Beta site APP cleaving enzyme 1,Beta site APP cleaving enzyme,Beta-secretase 1,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,FLJ90568,HSPC104,Memapsin 2,Memapsin-2,Memapsin2,Membrane associated aspartic protease 2,Membrane-associated aspartic protease 2,Transmembrane aspartic proteinase Asp2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BACE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
