Background：This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
仕様
Synonyms：Insulin gene enhancer protein ISL 1,Insulin gene enhancer protein ISL-1,Insulin related protein,ISL 1,ISL LIM homeobox 1,ISL1,ISL1 transcription factor LIM homeodomain,ISL1 transcription factor, LIM/homeodomain （islet 1）,ISL1 transcription factor, LIM/homeodomain,ISL1,Islet-1,Islet1
Host：Rabbit
Reactivity：Human
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human ISL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：200
Gene_ID（human）：3670
Swissprot：P61371
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Developmental biology, Neuroscience, Stem cells
