Background:This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms:DDX36,DEAH box protein 36,Dhx36,DHX36,EC 3.6.1.-,KIAA1488,MLE like protein 1,MLE-like protein 1,MLEL1,Probable ATP dependent RNA helicase DHX36,Probable ATP-dependent RNA helicase DHX36,RHAU,RNA helicase associated with AU rich element ARE ,RNA helicase associated with AU-rich element ARE
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DHX36
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000
Gene_ID(human):170506
Swissprot:Q9H2U1
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling