Background:The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:MMDS3,MVti1,SNARE Vti1a beta protein ,Vesicle transport through interaction with t-SNAREs homolog 1A,Vesicle transport through interaction with tSNAREs homolog 1A (yeast),Vesicle transport v-SNARE protein Vti1-like 2,Vti1 rp2,Vti1-rp2,Vti1a,VTI1A vesicle transport through interaction with t-SNAREs 1A,VTI1A,VTI1RP2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human VTI1A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.