Background:This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:AGS1,ATIP,ATM and Rad3 related interacting protein,ATM and Rad3-related-interacting protein,ATR interacting protein,ATR-interacting protein,Atrip,ATRIP,DKFZp762J2115,FLJ12343,MGC20625,MGC21482,MGC26740
Host:Rabbit
Reactivity:Human
Applications:IP
Concentration:1mg/ml
Immunogen:Recombinant protein of human ATRIP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.