Background：Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
仕様
Synonyms：Cernunnos,FLJ12610,NHEJ 1,Nhej1,NHEJ1, S. cerevisiae, homolog of,NHEJ1,Non homologous end joining factor 1,Non-homologous end-joining factor 1,Nonhomologous end joining factor 1,OTTHUMP00000164168,OTTHUMP00000206275,OTTHUMP00000206279,Protein cernunnos,XLF,XRCC4 like factor,XRCC4-like factor
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human NHEJ1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：200 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：79840
Swissprot：Q9H9Q4
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
