Background:This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
仕様
Synonyms:Carnitine O octanoyltransferase,COT,CROT,OCTC,Peroxisomal carnitine acyltransferase,Peroxisomal carnitine O octanoyltransferase,Peroxisomal carnitine O-octanoyltransferase
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human CROT
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):54677
Swissprot:Q9UKG9
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction, Tags & Cell Markers