Background:The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Carbonyl reductase 2,Carbonyl reductase II,DCR ,Dcxr,DCXR,Dicarbonyl and L xylulose reductase,Dicarbonyl L xylulose reductase,Dicarbonyl/ L xylulose reductase,Dicarbonyl/L-xylulose reductase,HCR2,HCRII,Human carbonyl reductase 2,kiDCR,Kidney dicarbonyl reductase,L xylulose reductase,L-xylulose reductase,P34H,PNTSU,SDR20C1,Short chain dehydrogenase/reductase family 20C member 1,Sperm surface protein P34H,XR
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DCXR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):51181
Swissprot:Q7Z4W1
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction