Background:The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).
仕様
Synonyms:AF4/FMR2 family member 4,AF5Q31,Alf4,ALL1 fused gene from chromosome 5q31,CHOPS,HSPC092,Laf4,Lymphoid nuclear protein related to AF4 like,Major CDK9 elongation factor associated protein ,MCEF,MGC107469,RP23-226J16.7
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human AFF4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):27125
Swissprot:Q9UHB7
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling