Background:The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
仕様
Synonyms:AMY 1,AMY-1,AMY1,Associate of Myc 1,C myc binding protein ,C-Myc-binding protein,Cmyc binding protein,MYCBP,MYCBP
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human MYCBP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):26292
Swissprot:Q99417
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling