Background:This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
仕様
Synonyms:Ataxin 10,Ataxin-10,ATX10,Atxn10,Brain protein E46 homolog,E46L,FLJ37990,HUMEEP,Like mouse brain protein E46,OTTHUMP00000197383,SCA10,Spinocerebellar ataxia 10,Spinocerebellar ataxia type 10 protein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human ATXN10
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.